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Richard J. Pisani, MD, Woodinville, WA
PURPOSE: It has been postulated that OSA severity is modified by weight reduction. We retested OSA patients who have successfully lost weight to determine the impact of weight loss on AHI.
METHODS: Patients were selected based on having an established diagnosis of OSA [defined by AHI >=5] and successful reduction in symptoms using CPAP. To be included in this study, they had to have lost more than 5 kg of weight since the time of the diagnosis. Testing was performed using an Edentrace Level III monitor.
RESULTS: Ten patients with an average age of 41.4 years and average body mass index [BMI] of 38.16 are reported on. There were 7 males and 3 females. Average weight loss between diagnosis and restudy was 23.3kg with a range of 7kg to 62.5kg. The average baseline AHI was 31 events per hour and the average AHI after weight reduction was 8.6 events per hour. Our patients, therefore, demonstrated a reduction of their AHI from baseline by 22.4 events per hour. The average time between initial diagnostic test and retest at lower body weight was 21.2 months.
CONCLUSION: Body weight reduction produces a significant reduction in OSA physiologic severity as measured by the AHI.
CLINICAL IMPLICATIONS: Sleep physicians often counsel patients with OSA to lose weight. We can estimate that with the reduction in AHI they will see on average one less event per hour per each kg of weight lost.
DISCLOSURE: R.J. Pisani, None.
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